Endocrine Abstracts

Shapiro's syndrome is characterised by agenesis of the corpus callosum, hypothermia and hyperhydrosis. We report a case associated with abnormal water balance and hypothalamic dysfunction.A 20 year old Turkish Cypriot man presented with an 8 month history of profuse sweating associated with a perception of extreme cold. He described progressive problems with speech, memory and clumsiness on walking. Symptoms of polyuria and polydipsia were associated wit...